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David Trew

Consulting Ltd

Controlling Chromatographic Integration in a Regulated or Accredited Laboratory

The proper measurement (integration) of the peak areas in analytical chromatograms often calls for the analytical chemist to make judgements regarding accurate and consistent integration. As with many processes calling for human judgement there is the potential for this judgement to be influenced by non-objective criteria. This article discusses the application of objective and scientifically sound processes to yield chromatographic integration that can withstand scientific and regulatory scrutiny.